Macrogen, Inc. Certified as NimbleGen Array Service Provider for Korea

(PresseBox) (Madison, WI, USA, ) Roche NimbleGen (SIX: RO, ROG; OTCQX: RHHBY) announced today that Seoulbased genomic services provider Macrogen, Inc. has officially joined the Roche NimbleGen Certified Service Provider (CSP) Program. Macrogen has been certified to process customer samples for NimbleGen Comparative Genomic Hybridization/Copy Number Variation (CGH/CNV) services in their lab in Seoul. As a CSP, Macrogen will process gDNA samples for CGH/CNV using the complete NimbleGen array CGH workflow which includes the highresolution NimbleGen MS 200 Microarray Scanner. Due to the company's previous experience using NimbleGen arrays and their certification as a service provider, Macrogen will be able to provide an extremely high level of array service to customers for highthroughput array and data processing. Macrogen had successfully finished the Korea Centers for Disease Control and Prevention (KCDC) CNV projects using Roche NimbleGen aCGH microarrays in 2009. The KCDC CNV project was twophase study including largescale characterization of CNVs in Korean populations and analysis of common CNVs in genomewide association studies for 6,000 Korean individuals.

CGH is an important tool that allows the detection of chromosomal abnormalities, copy number variations, and specific breakpoints at much higher resolution over conventional methods. The genomewide and disease associated region focused research that this technology provides on these types of chromosomal phenomenon has the potential to bring significant advances into the development of personalized healthcare options in the future.

"Macrogen is a leading service provider for CNV analysis based on several significant studies completed including the KCDC project targeting Koreanspecific CNVs as well as the world's first highdefinition Asian CNV map." said Dr. Hyungtae Kim, CEO of Macrogen. "I believe that Roche NimbleGen's CGH/CNV microarrays allow Macrogen to remain at the cuttingedge with the latest technologies for CNV studies to provide our customers with a leading microarray service."

"Roche NimbleGen is extremely pleased to welcome Macrogen as our first certified service provider in Korea for the CGH/CNV application. We look to build on our recent KCDC collaboration with Macrogen, which used our high resolution CNV arrays, to strengthen our global position in the field of copy number variation detection" said Dr. Frank Pitzer, CEO of Roche NimbleGen, Inc.

For more information about Roche NimbleGen, please visit www.nimblegen.com

About Macrogen

Macrogen, Inc., Seoul Korea, a world leading service provider in the highquality gene analysis, has enjoyed stable and steady growth since 1997 and gained worldwide recognition as a bioengineering company offering comprehensive services in genetic information analysis. Knowing that the 21st century medical revolution requires new genomicbased tools, the company has dedicated itself to providing the fundamental research and development tools such as bioinformatics infrastructure for genetic information analysis and functional genomics. The company offers DNA sequencing, next generation sequencing, microarray service and analysis, and genetically engineered mice services. In addition, Macrogen has been actively expanding its business scope into molecular diagnostics and personal genomics. With a global presence, Macrogen operates through its subsidiaries in Rockville, MD in the U.S., in The Netherlands in Europe, and in Tokyo, Japan. Macrogen is listed on the Korea Securities Dealers Automated Quotation (ticker symbol: A038290). For more information, visit www.macrogen.com.

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Roche Diagnostics Deutschland GmbH
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Kary Staples
Roche NimbleGen
Dr. Burkhard Ziebolz
Roche Applied Science
Head Global Communication
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